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王冰 | |||
性 别: | 男 | 职 称: | 教育,高等学校教师,教授 |
籍 贯: | 陕西省 西安市 | 现 居 地: | |
毕业院校: | 无 | 专 业: | |
查看更多个人信息 | |||
出生年月: | 工作单位: | 西安交通大学医学院 | |
邮 箱: | wangbing@mail.xjtu.edu.cn | 联系电话: | |
学 历: | 博士 |
【人物简介】
王冰,男,博士,高级职称,九三学社。国家级创新药物孵化基地"创新多肽药物研究与孵化基地"牵头人之一,卫生部第三类医疗技术审核委员会委员。医疗器械评审委员会委员。新型治疗性疫苗工程中心(省部级)主任,西安交通大学医学院科研部主任。"十一五"863专项项目"脑血栓治疗新方法--多肽纳米脂质微泡"组长。国家重大传染病项目专家,国家自然科学基金评审专家,教育部博士点、新教师基金评审专家。中华医学会会员。
【研究方向】
1、心血管分子病理学研究 2、创新多肽药物关键技术与新药研发;3、重大疾病治疗性多肽分子修饰疫苗的研究;新型药物转运载体的研究,新型"微泡联合低频超声主动靶向溶栓系统"的研究。
【研究成果】
【科研项目】
【论文著作】
代表性论文: 1.Thrombolysis effect of a novel targeted microbubble with low-frequency ultrasound in vivo. Thrombosis and Haemostasis 2008(9)100 2: 356-361. (IF: 6.094) 2.Antithrombotic effect of Z4A5 on coronary thrombosis in a canine model of acute unstable angina [J]. Br J Pharmacol, doi: 10.1111/bph.12026, (2013) 169 848–859 (IF: 5.067) 3.The Antitumor Effect of a New Docetaxel-Loaded Microbubble Combined with Low-Frequency Ultrasound In Vitro: Preparation and Parameter Analysis. Pharm Res (2013) 30:1574–1585. DOI 10.1007/s11095-013-0996-5. (IF: 4.742) 4. A novel anti-platelet peptide (Z4A5) specific for glycoproteinⅡb/Ⅲa inhibits platelet aggregation, Thrombosis Research 2012, 129(5): E217-E222. (IF: 3.133) 5.Antithrombotic activity of Z4A5, a new platelet glycoprotein IIb/IIIa receptor antagonist evaluated in a rabbit arteriovenous shunt thrombosis model. Thrombosis Research 128 (2011)。 463-469. (IF: 3.133) 6.The preparation of a new self-made microbubble-loading urokinase and its thrombolysis combined with low-frequency ultrasound in vitro [J]. Ultrasound in Medicine and Biology, Vol. 37, No. 11 on pages 1828-1837. (IF2.493) 7.Thrombolytic effects of a combined therapy with targeted microbubbles and ultrasound in a 6-hour cerebral thrombosis rabbit model [J]. Journal of Thrombosis and Thrombolysis 2012, 33(1): 74-81. (IF: 1.985) 8.Platelet-targeted microbubbles inhibit re-occlusion after thrombolysis with transcutaneous ultrasound and microbubbles. Ultrasonics 51 (2011) 270–274. (IF: 2.028) 9. Liraglutide ameliorates glycometabolism and insulin resistance via GLUT4 up-regulation in diabetic KKAy mice. Int J Mol Med, 2013, 32(4): 892-900. PMID: 23877319 (IF: 1.957 )