【人物简介】

　　赵新锋，西北大学讲师。西安交通大学博士毕业，2009年开始在西北大学任教，主要从事生物样品分析新方法，血管新生模型与中药活性成分研究工作。

【研究方向】

血管新生模型与中药活性成分。

【研究成果】

　　专利： 　　1、 β-(3,4-二羟基苯基)-α-羟基丙酸异丙酯及其合成方法. 专利号：ZL. 200410026205.3，授权日期： 2008.12.10 　　2、 β-(3,4-二羟基苯基)-α-羟基丙酸冰片酯、其合成方法和用途，专利号：ZL. 200610042787.3,授权日期： 2008.09.03

【科研项目】

　　1、 国家自然科学基金项目：固定化功能蛋白质取向及构象表征和调控色谱新方法(编号：21005060)，起止时间：2011.1~2013.12，项目负责人 　　2、 中国科学院“西部之光人才培养计划”项目：Alpha1A-肾上腺素受体色谱的建立及其在心血管药物活性成分筛选中的应用(编号：2007DF02)，起止时间：2008.01~2010.12，项目负责人 　　3、 国家重大新药创制专项项目：“抗脑缺血1类化学新药DBZ的开发”(编号：2009ZX09103-121)，起止时间：2009.1~2010.12，项目组副组长 　　4、 国家重大新药创制专项项目：“基因重组血管生长抑制剂Kringle 5的中试生产工艺和药用研究”(编号：2009ZX09103-696)，起止时间：2009.1~2010.12，项目组副组长

【论文著作】

　　1、 Zhao XF, Nan YF, Xiao CN, Zheng JB, Zheng XH, Wei YM, Zhang YY. Screening the bioactive compounds in aqueous extract of Coptidis rhizome which specifically bind to rabbit lung tissues β2-adrenoceptor using an affinity chromatographic selection method, Journal of Chromatography B, 2010, 878:2029-2034 　　2、 Zhao XF, Nan YF, Li J, Li YF, Bian LJ, Zheng XH. Effects of pH and ionic strength on the interaction between ligands and immobilized β2-adrenoceptor,Advances in Biomedical Research, 2010, 202-204 　　3、 王晓雯，张 鹏，左 燕，李易非，张亚军，赵新锋*.高效液相色谱-二极管阵列-离子阱质谱法对红花水提物中有效成分群的定性分析,中国药业，2010,19(15)：8-9 　　4、 Nan YF, Zhao XF, Wei LS, Wang HF, Xiao CN, Zheng XH. Determination of jasminoidin in rabbit plasma for the pharmacokinetic investigation after single dose oral administration of Gardenia jasminoides Ellis and Gardenia jasminoides Ellis coupling Coptis chinensis Franch extracts, Chromatographia, 2010, 71(11-12): 1031-1037 　　5、 Nan YF, Zhang QZ, Shen XJ, Zhao XF, Zheng XH. Isopropyl 3-(3,4-dihydroxyphenyl)-2-hydroxypropanoate, Acta Crystallographica Section E, 2010, E66, o1105. 　　6、 Zhao XF, Zheng XH, Wei YM, Bian LJ, Wang SX, Zheng JB, Zang WJ, Li ZJ, Zhang, YY. Thermodynamic study on the interaction between terbutaline and salbutamol with an immobilized β2-adrenoceptor by high-performance liquid chromatography. Journal of Chromatography B, 2009, 877: 911-918 　　7、 Zhao XF, Zang WJ, Kong SS, Zheng XH, Zheng JB, Shi RJ. A valid assay for pharmacokinetic study on gallic acid incherospondiatis fructus in rabbit plasma. Journal of Liquid Chromatography & Related Technologies, 2007, 30(2): 235-244. 　　8、 Zhao XF, Zang WJ, Zheng XH, Zheng JB. High performance liquid chromatography – atmospheric pressure chemical ionization – trap mass assay for pharmacokinetics study of Amygdalin in rabbit plasma. Chromatographia, 2007, 65(3-4): 149-153. 　　9、 Zheng XH, Zhao XF, Yang R, Wang SX, Wei YM, Zheng JB. β2-Adrenoceptor affinity chromatography and its application in the screening of the active compounds from Semen Armeniacae Amarum, Chinese Science Bulletin, 2008, 53(6): 842-847. 　　10、 Liu J, Zhao XF, Zhang L, Fang MF, Sun WJ, Zheng XH. Co-administration of Radix curcumae alters the tissue Distribution of Danshensu in Radix Salviae miltiorrhiza in rabbits. American Journal of Chinese Medicine, 2008, 36(5): 929-938 　　11、 Zhang QZ, Li ZJ, Zhao XF, Wang SX, Zheng XH. Analysis of isopropyl-3-(3, 4-dihydro-xyphenyl)-2- hydroxypropanoate, a novel metabolite from Danshensu in Salvia miltiorrhiza, in Rabbit Plasma. Chromatographia, 2008, 68: 1067-1070. 　　12、 Zheng XH, Zhao XF, Zhao X, Wang SX, Wei YM, Zheng JB. Determination of the main bioactive metabolites of Radix Salvia miltiorrhizae in compound Danshen Dripping Pills and the tissue distribution of danshensu in rabbit by SPE-HPLC-MSn. Journal of Separation Science, 2007, 30: 851-857 　　13、 Zheng XH, Zhao XF, Wang SX, Luo K, Wei YM, Zheng JB. Co-administration of Dalbergia Odorifera increased bioavailability of Salvia Miltiorrhizae in healthy and qi-stagnancy and blood stasis rabbit. American Journal of Chinese Medicine, 2007, 35(5): 831-840. 　　14、 Wang SP, Zang WJ, Kong SS, Yu XJ, Sun L, Zhao XF, Wang SX, Zheng XH. Vasorelaxant effect of isopropyl 3-(3, 4-dihydroxyphenyl)-2-hydroxypropanoate, a novel metabolite from salvia miltiorrhiza, on isolated rat mesenteric artery. European Journal of Pharmacology, 2008, 579: 283-288