【人物简介】

　王建国，男，1986年6月生，甘肃通渭人，中共党员，博士，副教授，硕士生导师。 　　二、教育及工作经历 　　教育经历： 　　2008年7月毕业于山西农业大学动物医学专业，获农学学士学位 　　2013年6月毕业于吉林大学临床兽医学专业，获农学博士学位 　　工作经历： 　　2013年7月至2017年12月在西北农林科技大学动物医学院任讲师 　　2018年1月至今在西北农林科技大学动物医学院任副教授

【研究方向】

畜禽重要群发性营养代谢病病因学、致病机制及综合控技术研究。

【研究成果】

　近年来，先后在Journal of Dairy Research、Molecular and Cellular Biochemistry、Journal of Comparative Pathology和《中国兽医学报》等期刊发表论文30余篇，其中以第一作者或通讯作者发表SCI收录论文20余篇，教学改革论文3篇，参编著作4部。

【科研项目】

　近5年主持的代表性科研项目： 　　国家自然科学基金青年基金项目——NEFA介导内质网应激对奶牛肝细胞自噬和脂质代谢的调控机制 　　陕西省农业科技创新与攻关项目——围产期奶牛酮病群体监测技术研究与示范推广 　　中国博士后基金面上项目（一等资助）——NEFA介导内质网应激对奶牛肝细胞凋亡和脂质代谢的影响 　　陕西省博士后（国家自然科学基金）专项配套经费 　　陕西省专项配套经费——能量负平衡介导内质网应激调控奶牛肝脂代谢的分子机制 　　陕西省博士后基金面上项目（二等资助）——非酯化脂肪酸介导内质网应激调控奶牛肝细胞自噬和凋亡的分子机制 　　中央高校基本科研业务费——ANGPTL4过表达对奶牛肝细胞脂质代谢的影响及其分子机制 　　西北农林科技大学博士科研启动经费——围产期奶牛血液能量代谢相关指标比较与分析

【论文著作】

　　Chuanjiang Cai, Yezi Kong, Dianjun Wu, Jianguo Wang*(通讯作者). Evaluation of changes in the levels of serum macromineral elements and calcitropic hormones in periparturient dairy cows and cows with subclinical hypocalcemia. Journal of Dairy Research, 2018, 85:12-15. 　　Wang Jianguo*, Guo Yazhou, Kong Yezi, Dai Shaohua, Zhao Baoyu*. High non-esterified fatty acid concentrations promote expression and secretion of fibroblast growth factor 21 in calf hepatocytes cultured in vitro . Journal of Animal Physiology and Animal Nutrition, 2018, 102(1):e476-e481. 　　Yezi Kong, Yazhou Guo, Jinfeng Zhang, Baoyu Zhao, Jianguo Wang*(通讯作者). Strontium promote transforming growth factor β1 and β2 expression in rat chondrocytes cultured in vitro . Biological Trace Element Research, 2017, DOI: org/10.1007/s12011-017-1208-7. 　　Jianguo Wang, Xiaoyan Zhu, Yazhou Guo, Zhe Wang, Baoyu Zhao*, Yunhou Yin, Guowen Liu*. Influence of dietary copper on serum growth-related hormone levels and growth performance of weanling pigs. Biological Trace Element Research, 2016, 172(1):134-139. 　　Jianguo Wang, Xiaoyan Zhu, Zhe Wang, Junhu Yao*, Baoyu Zhao*, Guowen Liu*. Non-esterified fatty acids promote expression and secretion of angiopoietin-like protein 4 in calf hepatocytes cultured in vitro. Molecular and Cellular Biochemistry, 2015, 401:141-146. 　　Jianguo Wang, Xiaoyan Zhu, Zhe Wang, Xiaobing Li, Baoyu Zhao*, Guowen Liu*. Changes in serum copper and zinc levels in healthy and subclinically hypocalcemic peripartum dairy cows. Biological Trace Element Research, 2014, 159(1-3):135-139. 　　Jianguo Wang, Xiaoyan Zhu, Lei Liu, Xiaoxia Shi, Liheng Yin, Yuming Zhang, Xiaobing Li, Zhe Wang*, Guowen Liu*. Effects of strontium on collagen content and expression of related genes in rat chondrocytes cultured in vitro . Biological Trace Element Research, 2013, 153(1-3):212-219. 　　Jianguo Wang, Xiaoyan Zhu, Guanghong Xie, Yonghong Zhang, Zhaoxi Liu, Liang Zhang, Chenxu Zhao, Wentao Yang, Xiaoxia Shi, Zhe Wang, Guowen Liu*. Effect of insulin-like growth factor-1 (IGF-1) on the gluconeogenesis in calf hepatocytes cultured in vitro . Molecular and Cellular Biochemistry, 2012, 362:87-91. 　　Jianguo Wang, Xiaoyan Zhu, Guanghong Xie, Yonghong Zhang, Zhaoxi Liu, Liang Zhang, Chenxu Zhao, Wentao Yang, Xiaoxia Shi, Zhe Wang, Guowen Liu*. Effect of copper on the expression of IGF-1 from chondrocytes in newborn piglets in vitro . Biological Trace Element Research, 2012, 148:178-181. 　　Jianguo Wang, Xiaoyan Zhu, Xiaobing Li, Wei Wang, Xiaoxu Wang, Lei Liu, Qinghua Deng, Ge Bai, Jianfa Wang, Haihua Feng, Zhe Wang, Guowen Liu*. Effects of copper on proliferation and autocrine secretion of insulin-like growth factor-1 (IGF-1) and IGF-binding protein-3 (IGFBP-3) in chondrocytes from newborn pigs in vitro . Biological Trace Element Research, 2011, 144:588-596. 　　Wenyan Yang, Jianguo Wang, Lei Liu, Xiaoyan Zhu, Xiaoxu Wang, Zhaoxi Liu, Zhe Wang, Lianyu Yang, Guowen Liu*. Effect of high dietary copper on somatostatin and growth hormone-releasing hormone levels in the hypothalami of growing pigs. Biological Trace Element Research, 2011, 143:893-900.（共同一作） 　　Xiaoyan Zhu, Jianguo Wang, Guanghong Xie, Haihua Feng, Xiaobing Li, Lei Liu, Xiaoxu Wang, Dongna Li, Zhaoxi Liu, Jian Qian, Zhe Wang, Guowen Liu*. Effect of copper on the expression of TGF-β in incubated chondrocytes of newborn pigs. Biological Trace Element Research, 2011, 143:1461-1469.（共同一作） 　　Xue Yuan, Jianguo Wang, Xiaoyan Zhu, Zhigang Zhang, Yongxing Ai, Guoquan Sun, Zhe Wang, Guowen Liu*. Effect of copper on levels of collagen and alkaline phosphatase activity from chondrocytes in newborn piglets in vitro . Biological Trace Element Research, 2011,144:597-605.（共同一作） 　　Wenyan Yang, Jianguo Wang, Xiaoyan Zhu, Yunhang Gao, Zhaoxi Liu, Liang Zhang, Hui Chen, Xiaoxia Shi, Lianyu Yang, Guowen Liu*. High lever copper promote ghrelin gene expression in the fundic gland of growing pigs. Biological Trace Element Research, 2012, 150(1-3):154-157.（共同一作） 　　WANG Jian-guo, ZHU Xiao-yan, WU Dian-jun, LIU Guo-wen*. Bone morphogenetic proteins and bone metabolism. Animal Husbandry and Feed Science, 2011, 3(2):12-14. 　　Zhigang Zhang, Jianguo Wang*, Ruifeng Gao, Weiqiang Zhang, Xinwei Li, Guowen Liu, Xiaobing Li, Zhe Wang, Xinglin Zhu. High-energy diet at antepartum decreases insulin receptor gene expression in adipose tissue of postpartum dairy cows. Bulletin of the Veterinary Institute in Pulawy, 2013, 57(2):203-207. 　　Guowen Liu, Zhigang Zhang, Jianguo Wang, Zhe Wang*, Chuang Xu, Xinglin Zhu. Insulin receptor gene expression in normal and diseased bovine liver. Journal of Comparative Pathology, 2010, 143(4): 258-261. 　　参编著作： 　　《天然草原牲畜毒害草中毒防治技术》, 西北农林科技大学出版社, 2017. 　　《中国天然草原毒害草综合防控技术》, 中国农业出版社, 2016. 　　《中国天然草地有毒有害植物名录》, 中国农业科学技术出版社, 2016. 　　《中国重要有毒有害植物名录》, 中国农业科学技术出版社, 2015. 　　教学改革项目及课程建设： 　　OIA课程设计和BOPPPS教学模式在《兽医内科学》教学中的探索与实践, 西北农林科技大学教学改革项目（主持）. 　　《兽医内科学》在线课程建设（SPOC）（主持）. 　　《家畜内科学》函授教育网络课程建设（参与）.