【人物简介】

医学博士，副教授，为2008年全国百篇优秀博士论文获得者。2006年毕业于第四军医大学获得博士学位。

【研究方向】

长期从事胃癌恶性生物学行为尤其是转移分子调控机理研究。

【研究成果】

执行主编专著3本，参编专著3本。共发表SCI论文37篇。

【科研项目】

曾完成国家自然科学基金青年项目1项，现负责在研面上项目1项，参加973课题以及多项国家自然科学基金重点及面上项目的研究工作。

【论文著作】

1. Tie J, Pan Y（co-first author）, Zhao L, Wu K, Liu J, Sun S, Guo X, Wang B, Gang Y, Zhang Y, Li Q, Qiao T, Zhao Q, Nie Y, Fan D. MiR-218 inhibits invasion and metastasis of gastric cancer by targeting the Robo1 receptor. PLoS Genet. 2010 Mar 12;6(3):e1000879. （IF=8.88） 2. Zhao L, Pan Y（co-first author）, Gang Y, Wang H, Jin H, Tie J, Xia L, Zhang Y, He L, Yao L, Qiao T, Li T, Liu Z, Fan D. Identification of GAS1 as an epirubicin resistance-related gene in human gastric cancer cells with a partially randomized small interfering RNA library. J Biol Chem. 2009; 284:26273-85 （IF=5.52） 3. Li X, Pan Y, Fan R, Jin H, Han S, Liu J, Wu K, Fan D. Adenovirus-delivered CIAPIN1 small interfering RNA inhibits HCC growth in vitro and in vivo. Carcinogenesis. 2008; 29:1587-93 4. Pan Y, Zhao L, Liang J, Liu J, Shi Y, Liu N, Zhang G, Jin H, Gao J, Xie H, Wang J, Liu Z, Fan D. Cellular prion protein promotes invasion and metastasis of gastric cancer. FASEB J. 2006; 20: 1886-1888. （IF=7.06） 5. Pan Y, Bi F, Liu N, Xue Y, Yao X, Zheng Y, Fan D. Expression of seven main Rho family members in gastric carcinoma. Biochem Biophys Res Commun. 2004; 315: 686-691. （IF=2.90） 6. Pan Y, Zhao L, Liu Z, Liu N, Jin H, Zhang G, Liu J, Wang J, Lin T, Sun L, Qiao T, Wang J, and Fan D. KCNE2, a down-regulated gene identified by in silico analysis, suppressed proliferation of gastric cancer cells. Cancer Lett, 2007; 246: 129-38. （IF=3.40） 7. Jin H, Pan Y（co-first author）, Zhao L, Zhai H, Li X, Sun L, He L, Chen Y, Hong L, Du Y, Fan D. p75 neurotrophin receptor suppresses the proliferation of human gastric cancer cells. Neoplasia. 2007; 9: 471-478. （IF=5.67） 8. Jin H, Pan Y（co-first author）, He L, Zhai H, Li X, Zhao L, Sun L, Liu J, Hong L, Song J, Xie H, Gao J, Han S, Li Y, Fan D. p75 neurotrophin receptor inhibits invasion and metastasis of gastric cancer. Mol Cancer Res. 2007; 5: 423-433. （IF=4.32） 9. Liang J, Pan Y, Zhang D, Guo C, Shi Y, Wang J, Chen Y, Wang X, Liu J, Guo X, Chen Z, Qiao T, Fan D. Cellular prion protein promotes proliferation and G1/S transition of human gastric cancer cells SGC7901 and AGS. FASEB J. 2007; 21: 2247-2256. （IF=6.7） 10. Liang J, Pan YL, Ning XX, Sun LJ, Lan M, Hong L, Du JP, Liu N, Liu CJ, Qiao TD, Fan DM. Overexpression of PrPC and its antiapoptosis function in gastric cancer. Tumour Biol. 2006, 27: 84-91. 11. Du J, Pan Y, Shi Y, Guo C, Jin X, Sun L, Liu N, Qiao T, Fan D. Overexpression and significance of prion protein in gastric cancer and multidrug-resistant gastric carcinoma cell line SGC7901/ADR. Int J Cancer. 2005, 113: 213-220.