【人物简介】

　　赵燕，博士，第四军医大学药学系化学教研室副教授，硕士研究生导师。主要从事药物分析研究。

【研究方向】

1.毛细管电泳手性药物的质控检测 2.新型手性选择剂的设计、合成及性能研究 3.体内Biomarker代谢分析

【研究成果】

【科研项目】

　　负责国家自然科学基金与陕西省科技攻关基金各1项，参加国科金与省基金研究多项。

【论文著作】

　　1. Yan Zhao, Emilie Mas, Trevor A. Mori, Kevin D. Croft, Anne E. Barden*. A significant proportion of F2-isoprostanes in human urine are excreted as glucuronide conjugates. Analytical Biochemistry, 2010,403:126–128 　　2 Xingbin Yang, You Lv, Lingmin Tian, Yan Zhao*. Composition and systemic immune activity of the polysaccharides from an herbal tea, the leaves of Lycopus lucidus Turcz. Journal of Agricultural and Food Chemistry, 2010, 58:6075–6080 （Corresponding author） 　　3. Yan Zhao, Xingbin Yang, XiaoLi Sun, Ru Jiang, Shengyong Zhang. Enantiomeric separation of synthetic 2,3-dihydroxy-3-phenylpropionate compounds by β-cyclodextrin -modified capillary electrophoresis. Journal of Chromatography A, 2006, 1108:258-262 　　4. Yan Zhao, Xingbin Yang, Ru Jiang, Xiaoli Sun, Xiaoye Li, Wenmin Liu, Shengyong Zhang. Analysis of optical purity and impurity of synthetic D-phenylalanine products using sulphated β-cyclodextrin as chiral selector by the reversed-polarity capillary electrophoresis. Chirality, 2006, 18: 84-90 　　5. Yan Zhao, Xingbin Yang, Qiaofeng Wang, Pengjuan Nan, Ying Jin, Shengyong Zhang. Determination of enantiomeric excess for 2,3-dihydroxy-3-phenylpropionate compounds by capillary electrophoresis using hydroxypropyl-β-cyclodextrin as chiral selector. Chirality, 2007, 19:380-385 　　6. Yan Zhao, Xingbin Yang, Ru Jiang, Xiaoli Sun, Wenmin Liu, Shengyong Zhang. Chiral separation of synthetic vicinal diol compounds by capillary zone electrophoresis with borate buffer and β-cyclodextrin as chiral selector. Analytical Sciences, 2006, 22:747-751 　　7. Yan Zhao, Xingbin Yang, Qiaofeng Wang, Xiaoli Sun, Ru Jiang, Shengyong Zhang. Determination enantiomeric excess of aromatic 1,2-diols with HP-β-cyclodextrin as chiral selector by capillary electrophoresis. Chromatographia, 2007, 66: 601-605 　　8.Yan Zhao, Li Liu, Xingbin Yang, Xiaoye Li, Wengmin Liu, Shengyong Zhang. Analysis of the monosaccharides in Rheum tanguticum polysaccharides by capillary zone electroresis. Chinese Journal of Analytical Chemistry, 2006, 34（2）：255-258 　　9.Yan Zhao, Xiaoli Sun, Xingbin Yang, Pengjuan Nan, Ying Jin, Shengyong Zhang. Enantiomeric separation and optical purity analysis of three arylethanediold by capillary zone electroresis. Chinese Journal of Analytical Chemistry, 2006, 34（3）：293-297 　　10 Xingbin Yang, Yan Zhao, Nianwu He, Kevin D. Croft*. Isolation, characterization, and immunological effects of α-galacto-oligosaccharides from a new source, the herb Lycopus Lucidus Turcz. Journal of Agricultural and Food Chemistry, 2010, 58, 8253-8258 　　11. Xingbin Yang, Yan Zhao, Guoli Li, Zhezhi Wang, You Lv. Chemical composition and immuno-stimulating properties of polysaccharide biological response modifier isolated from Radix A. sinensis. Food Chemistry, 2008, 106: 269-276 　　12. Xingbin Yang, Yan Zhao, You Lv. In vivo macrophage activation and physicochemical property of the different polysaccharide fractions purified from Angelica sinensis. Carbohydrate Polymers, 2008,71（3）：372-379 　　13 Xingbin Yang*, Yan Zhao, Ying Yang, Yun Ruan. Isolation and Characterization of Immunostimulatory Polysaccharide from an Herb Tea, Gynostemma pentaphyllum Makino. Journal of Agricultural and Food Chemistry, 2008, 56（16）： 6905-6909. 　　14. Xingbin Yang, Yan Zhao, You Lv. Chemical composition and antioxidant activity of an acidic polysaccharide extracted from Cucurbita moschata Duchesne ex Poiret. Journal of Agricultural and Food Chemistry, 2007, 55（12）： 4684-4690 　　15. Xingbin Yang, Yan Zhao, Haifang Wang, Qibin Mei. Macrophage activation by an acidic polysaccharide isolated from Angelica sinensis （Oliv.） Diels. Journal of Biochemistry and Molecular Biology, 2007, 40（5）： 636-643 　　16. Xingbin Yang, Yan Zhao, Yanjuan Zhou, You Lv, Jieli Mao, Ping Zhao. Component and antioxidant properties of polysaccharide fractions isolated from Angelica sinensis （Oliv.） Diels. Biological & Pharmaceutical Bulletin, 2007, 30 （10）： 1884-1890 　　17. Xingbin Yang, Yan Zhao, You Lv, Ying Yang, Yun Ruan. Protective effect of polysaccharide fractions from Radix A. sinensis against tert-butylhydroperoxide induced oxidative injury in murine peritoneal macrophages. Journal of Biochemistry and Molecular Biology, 2007, 40（6）：928-935 　　18. Xingbin Yang, Yan Zhao, Qinwei Wang, Haifang Wang, Qibing Mei. Analysis of the monosaccharide components of angelica polysaccharides by high performance liquid chromatography. Analytical Sciences, 2005, 21:1177-1180 　　19 Peng Liu, Wei He, Yan Zhao, Pingan Wang, Xiaoli Sun, Xiaoye Li, Shengyong Zhang. Synthesis of chiral vicinal diols and analysis of them by capillary zone electrophoresis. Chirality, 2008, 20:75-83 　　20 Mya Thida, John Earl, Yan Zhao, Hans Wang, Chi S. Tse, Janine J. Vickers, Matthew Sutton, Sharon L.H. Ong, Trevor A. Mori, Kevin D. Croft, Judith A. Whitworth and Yi Zhang. Effects of Sepiapterin Supplementation and NOS Inhibition on Glucocorticoid-Induced Hypertension. American Journal of Hypertension, 2010, 23（5）：569-574